HISTORY OF THE MEDICINAL USE OF TOBACCO/NICOTINE

[rickymouse]

Tobacco has been considered a medicine for centuries.  Nicotine is a big part of that, but there are also other chemicals in tobacco that have medical benefits too.  Nicotine is addictive, if I drink coffee, since I do not break down methyl well from the caffeine, I have to smoke a cigarette or I get the jitters.  I also had a chronic cough when I was younger, from youth through my twenties.  Then at thirty something I started to smoke and the chronic cough disappeared.  I actually breath easier smoking.  Now I cannot smoke the majority of cigarettes, I used to smoke Winstons and also some of the Native American full flavor cigarettes.  Now I smoke the sun grown Lorado.  What do those three have in common, hardly any additives.  Also, the filter tubes I use for the cigarettes...I noticed something...the ones I have been using all along that are easier on my lungs and to draw through....they all are manufactured in Canada.  Now the filter material approved in Canada is regulated and of higher quality, less plastic in the smoke I think.  So I use Zig-Zag, and Gambler usually.

Now Canada has rules that any cigarette tubes made there must have canadian certified filters in them, whether sold there or exported.  So the filters are less of a problem on my lungs is what I sense, and I did not even realize this till I started investigating the filters I have no problem with and the tubes I have more problems with.....It was the country of manufacturer.  Now I can try to find cheaper filter tubes made in Canada.  But with the import tax, all the canadian filters went up...good way to find out which are not produced in the USA.  I remember when filters were made from cotton or some bamboo product years back, now they are made of a plastic compound....but because my cigarettes only cost about a buck twenty five a pack, I don't even get close to the filter....smoking about half or a little over half of the cigarette is easier on the lungs.  I also am intolerant to Propylene glycol, a chemical they put in tobacco....so the more natural ones don't seem to have that.  Is pyrazine and propylene glycol related?  Well, the pyrazine is often mixed in propylene glycol so maybe that is where the pyrazine is added.

Now, if I don't drink coffee, I have no desire for a cigarette.  That is what brought me to search why, and I found out that both methyl and ethyl poisoning are treated with nicotine or nicotinic acid.  A cigarette brings the nicotine into the lungs, then into the blood and if you cannot break down methyl, the nicotine will quickly react with the methyl or ethyl and turn it into ammonia....hence, they made smoking in bars illegal, so they can give out more drunk driving tickets as a benefit...or just put on a patch.  When niacin is metabolized, it turns to nitric oxide...whether in the stomach or through digestive enzymes in saliva and probably in the lungs too.  too much can make you light headed or dizzy, because it lowers blood pressure quickly if you are dehydrated.

Man, I can go on and on with methods of action of chemicals we consume or in this case inhale that have effects on humans.

I am not sure but remembering that molybdenum can break down methyl groups also ?

Some types of methyl issues can be broken down with molybdenum supplements, but it does not work with me at all.  I have been taking a molybdenum supplement as part of my anti-epileptic treatment for years, and it doesn't seem to help me to break down methyl groups much.  But I do have some negatives in the MOCO genetics and maybe because of that, molybdenum might not work for that use.  It does help break down xanthians, but not caffeine.  The whole enzyme system has multiple enzymes involved, just to do a process, a disruption in one enzyme can lead to a disfunction of other enzymes down the road.  The molybdenum supplement somewhat helps my intolerance to aldehydes, but still will not take away the problem with three day hangovers off of three beers.  But it does help somewhat to dampen my response to aldehydes in perfumes.  Now I have moth a Moco deficiency and a deunct aldehyde dehydrogenase enzyme.  so that part is not helped.  I can break alcohol down well, but get left with aldehydes, and I smell like an old man after drinking, my liver might not be able to break down aldehydes, but my skin can eject it.  I try to avoid some of the foods that need the aldehyde enzymes and I don;t smell so much like an old man.  I hate that smell.  Aldehydes from fruits not so bad, I smell like the fruit.  But booze and beer, the alcohol metabolism leaves a lot of aldehydes.

Now that ability to break down methyls isn't a problem if you are working and sweating, I could outwork almost anyone I knew, and my workers knew I was a workaholic when I had my business.  So did my friends.  and my wife.  After working twelve hours I came home and worked on the cars, mowed the grass, cut firewood, and prepped for the crew for the next day.  The crew put in eight hours and went home, I would take little jobs after having some coffee at the restaurant...and go out and work another four hours  I would put in a garage door, storm door, or go help a friend put in a window or work on their house after work.  I also built things in my shop and in my spare time, I built my house, garages, storage building, and worked on my vehicles.  I suppose that genetics is good genetics if you want to work all the time.  As I was working, somehow the methyl was not a problem, only needed a cigarette if I took a break usually..which didn't happen very often being I loved to work.

Then I got epilepsy from a car accident...just think how hard it is to go from being always going, almost like speeding, then going to where if my brain got excited or if I work I would have partial seizures.  I had severe withdrawls when I could not work anymore.

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  I also am intolerant to Propylene glycol, a chemical they put in tobacco....so the more natural ones don't seem to have that.  Is pyrazine and propylene glycol related?  Well, the pyrazine is often mixed in propylene glycol so maybe that is where the pyrazine is added.

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Vaping is probably a bad juju no-go for you as well, since the nicotine in vapes is suspended in PG, with VG being another additive in the mixture. I know the mixture because Grace makes our own vape juice, which is why we have the USP grade nicotine to begin with.

So, when they ban flavored vapes - or maybe they already have... I don't get out much - we'll still be good to go, since we have enough stuff to make our own for the next 20 years.

I had to stop vaping, as it seemed to be gunking up my lungs far worse than even commercial tobacco does, and I blame the PG/VG mixture for that.

Smoking some home-grown rustica fixed that gunking-up problem for me by expelling the gunk..

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PG actually makes my lungs fill water logged.  It is an emulsifier.  It will bring things into the cells and into the circulatory system, basically increasing the intake of the chemicals going into the body.  When used on creams for the skin, it plumps up the cells making the skin smoother looking...so think about what it does to the cells of your lungs.  It makes them not work as well to get oxygen and I believe that would be the same for anyone.  In shampoos, it smooths my partly bald head, but it does not let the gasses of metabolism leave the area, so my head gets itchy and pinkish in color.  So relate that to your lungs, you do not just get oxygen from your lungs, they excrete lots of metabolic chemicals  that are formed from metabolic processes.  So swelling them up means that you are keeping metabolic toxins in your body.  Emulcifiers can be problematic, in fact, tomato chemistry is emulsifier chemistry too, and it causes hives for me if I over indulge in tomatoes...my forehead and in my hair I get some hives, and I get itchy in various places if I eat more than one meal with tomatoes in it.  It also causes issues in my gut if I eat too much tomatoes....  Tomatoes, like other emulsifiers, will allow oils to mix with water and increase absorption....think about that, why do we have high cholesterol from foods.  Other emulsifiers are things like carrageenan and even xanthian mum in Ice cream and heavy creams.  But xanthian gum has some beneficial properties...where I cannot find much good about carrageenan other than it can have some specific antiviral chemistries...but those antiviral chemistries from carrageenan are problably negated by the fact it is bringing in extra lipids into the blood stream....but that is just a hypothesis I created, I have not seen any testing done on that, only that it makes fats mix with water better and get absorbed better.