Quote:    A rapidly spreading outbreak of chikungunya fever has gripped southern China, with over 4,000 confirmed cases since early July. Yet the Chinese Communist Party (CCP) appears to be downplaying the crisis while enforcing costly quarantines on infected citizens.
   
    Originating in Foshan city in Guangdong Province, the mosquito-borne virus has now reached Guangzhou, Yangjiang and even the capital Beijing – raising fears of a wider epidemic. Local residents report being forced into mandatory hospital isolation at their own expense, a policy that echoes the CCP's controversial Wuhan coronavirus (COVID-19) lockdowns. With China's history of suppressing health data, the true scale of the outbreak remains uncertain.

Quote:    FDA Approves Vimkunya (chikungunya vaccine, recombinant) for Prevention of Disease Caused by Chikungunya Virus COPENHAGEN, Denmark, February 14, 2025 – Bavarian Nordic A/S (OMX: BAVA) announced today that the U.S. Food and Drug Administration (FDA) has approved Vimkunya (Chikungunya Vaccine, Recombinant) for injection, the first virus-like particle (VLP) single-dose chikungunya vaccine in the U.S. for persons 12 years of age and older.

Quote:    VLPs are useful as vaccines. VLPs contain repetitive, high density displays of viral surface proteins that present conformational viral epitopes that can elicit strong T cell and B cell immune responses.[sup][16][/sup] The particles' small radius of roughly 20-200 nm allows sufficient draining into lymph nodes. Since VLPs cannot replicate, they provide a safer alternative to attenuated viruses. VLPs were used to develop FDA-approved vaccines for Hepatitis B and human papillomavirus, which are commercially available.[sup][17][/sup]

Quote:    Therapeutic and imaging agents - VLPs are a candidate delivery system for genes or other therapeutics.[sup][13][/sup] These drug delivery agents have been shown to effectively target cancer cells in vitro.[sup][14][/sup] It is hypothesized that VLPs may accumulate in tumor sites due to the enhanced permeability and retention effect, which could be useful for drug delivery or tumor imaging.

Quote:    Assembly - The understanding of self-assembly of VLPs was once based on viral assembly. This is rational as long as the VLP assembly takes place inside the host cell (in vivo), though the self-assembly event was found in vitro from the very beginning of the study about viral assembly.[sup][33][/sup] Study also reveals that in vitro assembly of VLPs competes with aggregation[sup][34][/sup] and certain mechanisms exist inside the cell to prevent the formation of aggregates while assembly is ongoing.[sup][35][/sup]

(08-04-2025, 05:41 PM)Michigan Swamp Buck Wrote: Bill Gates genetically modifies mosquitoes, making you wonder if a dot can be connected here. Plus, he is a vaccine man, and I believe he wanted to create a GM mosquito that could inject a vaccine when it bites you.

(4 hours ago)F2d5thCav Wrote: This guy has just the fix for the virus.  Line up, he said it won't hurt a bit!